- About the programme
- Application system opens on 1 December 2022
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- Lenka Krajáková: Improper behavior of ethylene polymerization
- Erik Sonntag: ROBO-PHARMACIST: Automatic Compounding Line for Continuous Manufacturing of Personalized Multi-Component Capsules
- Karel Mařík: Thermographical observation of the distillation process
In article Solvatochromic Shift Enables Intracellular Fate Determination of Curcumin Nanocrystals (Part. Part. Syst. Charact. 12/2022) Denisa Lizoňová, Adéla Brejchová, Eva Králová, Jaroslav Hanuš, František Štěpánek from our department describe a methodology based on fluorescence microscopy, where curcumin nanocrystals can be distinguished from cell-dissolved curcumin due to differences in fluorescence emission spectra. Thanks to this, the curcumin in the cells is visualized as blue (thus blue macrophage) and nanocrystals as red. This process depends on nanocrystal surface stabilization.
25 GAČR (Czech Science Foundation) projects are heading to UCT Prague, 13 standard projects will have the main researcher from UCT Prague, and UCT is cooperating on another 12 projects. One of the supported projects will also be solved at our department. It is called "Development of inhalable carriers for in-situ production of natural antibiotics" and the principal investigator is Ing.Ondřej Kašpar, Ph.D. Congratulations!
I would like to invite you to our last departmental seminar of this calendar year, which will be held on Friday, 16 December at 11:00 am in the room B028, consisting of the three following talks:
1. Přemysl Richtr: Towards more efficient and stable zinc–air flow battery
2. Vojtěch Šálek: Mathematical modeling of fire spread
3. František Jonáš Rejl: Transfer characteristics of negative, neutral and positive system during distillation on structured packing
You are all cordially invited to join us, listen and discuss the research of our department. Again, snacks will be served, as well as tea and coffee, so do not forget to bring your cups, too!
With best regards,
Department of Chemical Engineering would like to invite you to a lecture by Dr. Hermann J. Feise from BASF company titled „Is a climate friendly chemical industry possible?“ which will be held on Monday, 5 December from 4 pm in Uhelna.
Is a climate friendly chemical industry possible?
The European Green Deal has firmly established the political intend to counteract climate change by reducing greenhouse gas emissions. Current actions focus on the energy and transportation industries. However, the producing industries will clearly become the next target areas for emission reductions. As a clear indication, the member states of the European Union have already initiated an Important Project of Common European Interest (IPCEI) on Hydrogen Technologies and Systems. This program does not only address hydrogen production and infrastructure as well as hydrogen propelled transportation, but also the use of hydrogen to transform the steel, chemical and cement industries.
please mark in your calendars that the next seminar of our department will be held on Friday, 11 November at 11:00 am in the room B028, consisting of the three following talks:
1. Lucie Mašková: Nature-based 3D bioprinted films for controlled in-situ synthesis of bactericides
2. Dominik Švára: Preparation of porous structures for drug delivery applications
3. Pavel Zelenka: CFD simulation of air-flow and cross-contamination in production space
You are all cordially invited to join us, listen and discuss the research of our department. Again, snacks will be served, as well as tea and coffee, so do not forget to bring your cups, too!
With best regards,
On October 5 - 8, 2022, the teambuilding event "Běstvina 2022" took place for students of the 1st year of the Master's degree in Chemical Engineering and Bioengineering. The event was attended by 32 students who stayed for three nights at the UCT Prague camp base in Běstvina and traveled by bus on the excursion every day. The program included a total of 6 industrial excursions (Škoda Auto, Synthesia, Kemwater ProChemie, Pardubice Brewery, wastewater treatment plant in Kutna Hora) and a block of presentations by representatives of the research groups of our department. The event was organized by Jitka Čejková.
Our PhD student Ondřej Rychecký and his friends founded the H2OPODAŘ association in 2017. The H2Ospodař project prepares and presents activities in the field of water management for schools, the public and institutions. The original goal of the project was to create an interactive traveling exhibition about the cycle of drinking water and better water management in households and in nature. Several dozen events take part in this exhibition every year. They also regularly visit primary and secondary schools and are striving to become an information and educational platform focused on the careful handling of water.
Now H2Ospodař has scored in the program Hello Země! The six-month journey to the gala evening was challenging. Of all the applications for this year's SDGs Awards 2022, first Hello bank! selected 15 projects that would deserve their financial support. Bank employees then sent 10 of them to the final, where their clients already decided. From the festive evening in the beautiful premises of the National Museum, the H2Ospodař delegation, accompanied by little droplet Jarmilka, received with great joy a check for 2nd place worth 300,000 CZK! This H2Ospodař activity award is greatly appreciated by the team members, largely because it was ordinary people from Hello bank!'s clientele who had the decisive say. It means that the activity of H2Ospodař is important.
Many congratulations to the awardees and many thanks for their activities and education on how to save water.
The Scientific and Management Board of the Neuron Endowment Fund awarded the best implementation of basic research into practice. The Neuron Award for connecting science and business was awarded to Pinflow energy storage (Juraj Kosek, Jiří Vrána, Petr Mazur a Jaromír Pocedič), a company specialising in the storage of energy in redox flow batteries.
please mark in your calendars that next seminar of our department will be held on Friday, 21 October at 11:00 am in the room B028 (ex-classroom B03 in the ground floor next to the Respirium), consisting of the three following talks:
- Simon Jantač: Electrostatic charging of powders: A perplexing multiphysics phenomenon
- Martin Bureš: From homogeneous to “colloidal” olefin polymerization catalysts: effect of mass transport limitations on reaction kinetics and polymer microstructure
- Elizaveta Mutylo: Multiple-Unit Dosage System: a flexible tool for combination therapy
You are all cordially invited to join us, listen and discuss the research of our department. Again, snacks will be served, as well as tea and coffee, so do not forget to bring your cups too!
With best regards,
The first renewed seminar of our department took place on Friday, 30 September at 11:00 am in room B028 (ex-classroom B03 in the ground floor next to the Respirium).
Three talks of our PhD students were presented:
- Marie Plachá: Pore-scale modelling of soot deposits and their impact on catalytic filter performance
- Petr Polezhaev: Characterization of ion-exchange particles as the major functional component of heterogeneous ion-exchange particles
- Charlie Maslen: Hydrogel microrobots
Organized by Sasha Zubov
Oratorium Marianum hall of the University of Wroclaw hosted the competition Falling Walls on Monday 26 September, 2022. The participants pitched their innovative ideas in just three minutes, showcasing a breakthrough that creates a positive impact on science and society. Our student Erik Sonntag presented "BREAKING THE WALL OF MEDICAL NON-COMPLIANCE" and took the 3rd place. Congratulations!
The University of Chemistry and Technology Prague celebrates its 70th anniversary this year. On this occasion, a paper (in Czech) by Jitka Čejková devoted to the Faculty of Chemical Engineering was prepared. First, the history of the faculty and the development of its departments is summarized. The faculty was established as the Faculty of Chemical Production, Automation and Economics in 1960 and it was renamed to the Faculty of Chemical Engineering in 1969. Further, the key scientists, teachers and deans are introduced and their contribution to the advancement of the faculty highlighted. The current offer of study programs (bachelor, master and doctoral) in both Czech and English is also listed.
Master's graduations took place on Wednesday, June 22, 2022. At the same time, the Betlemská Chapel hosted a ceremonial award with the medals of the Faculty of Chemical Engineering of three outstanding personalities who, with their scientific, pedagogical or organizational activities, contributed to the development of our faculty. Dean of the faculty prof. Michal Přibyl handed over the medal personally to doc. Pavel Chuchvalec from the Department of Physical Chemistry, doc. Jitka Čejková from the Department of Chemical Engineering and doc. Vladimír Scholtz from the Department of Physics and Measurement Technology.
Teachers from our department spent two half days out of Prague to intensively discuss about topics related to education and research at our Department of Chemical Engineering.
The linked conference SSCHE 2022 and PERMEA 2022 was organized by the Slovak Society of Chemical Engineering with assistance of the Institute of Chemical and Biochemical Engineering of the Slovak University of Technology. The conference took place in Tatranské Matliare on 23 - 26 May, 2022. There was a poster competition and the winner was our PhD student Pavel Krýsa from the group of Miro Šoóš. The title of his poster was "Modelling of Bubble Breakage and Coalescence in Stirred and Sparged Bioreactor Using the Euler-Lagrange Approach". The second place took Standa Chvíla from František Štěpánek group. The theme of his poster was "Screening, scale-up and preformulation tests of pharmaceutical drug nanocrystals". Congratulations!
- Ondřej Dupal (1st place)
- Lukáš Kamenský (2nd place)
- Lucie Večerková (3rd place)
- Dominik Králík (1st place)
- Lucie Pilíková (2nd place)
- Filip Zavřel (1st palce)
This year's defenses of the Process Projects took place on Tuesday, January 18, 2022 from 1:00 pm in the AII auditorium. Students presented the results of their work in the form of 15-minute presentations, followed by an equally long discussion. Representatives of 15 companies formerly or now cooperating with our department also took part in the defense.
The following 6 projects are summarized in the proceedings (in Czech only)
Optimalizace průtočného chlazení
Vliv kontaktu katalyzátoru se stěnou trubky v R302 na její lokální přehřátí
Spotřeba tepla – páry při hvozdění zeleného sladu ve sladovně Prazdroj
Plzeňský Prazdroj a.s.
Využití odpadního tepla z výroby
Synthos Kralupy a.s.
Optimalizace odpařovacího systému na výrobně ledku vápenatého v Lovochemie, a.s.
Study of urea melt transport
Casale Project a.s.
On Friday, December 3, 2021, the Study in Prague university consortium organized an award ceremony for the extraordinary scholarships of prof. Miroslav Vlček. Among the scholarship recipients at the Prague City Hall Mayor's Residence was a student of UCT Prague – Ashley George.
Miroslav Vlček's scholarship is awarded to commemorate a professor and longtime vice-rector for external relations of the Czech Technical University in Prague, who established and developed the Study in Prague project between 2015-2019. The merger of 7 Prague public universities contributed to a higher internationalization of the university environment and attracted hundreds of international students to the Czech capital.
This prize is presented to international degree-seeking students that, in addition to their study obligations, contribute to sharing the good name of universities in Prague. As a student ambassador, Ashley has been a long-term partner of the International Department. She is not only a reference point for prospective students, but also helps with the organization of promotional events, and participates in the integration process of incoming international students.
Study in Prague
At UCT Prague
Do you also want to get an internationally recognized degree? The admission procedure for English study programs at UCT Prague is open from January 15 to February 28, 2022. Visit our website study.vcht.cz for more information.
At other universities
If you are also interested in other fields of study at Prague universities, refer to the Study in Prague website directly.
Photo credit: Zuzana Markéta Macková, AMU
Many congratulations to a team of authors lead by Denisa Lizoňová for having their work titled “Multilobed Magnetic Liposomes Enable Remotely Controlled Collection, Transport, and Delivery of Membrane-Soluble Cargos to Vesicles and Cells” feature on the front cover of ACS Applied Bio Materials. The work described new multi-compartmental liposome structures that can transport both hydrophilic and lipophilic molecular payload by means of magnetic navigation. Crucially, the paper demonstrates the ability of these structures to deliver membrane-soluble substances to cancer cells with a high efficiency.
The head of our Department of Chemical Engineering, prof. Ing. František Štěpánek, Ph.D., is currently a visiting Fulbright Scholar at Rutgers University, New Jersey. Watch on a public talk "Trends and challenges of industrial pharmacy today" as a part of Czech Science Café New York.
Student of the second year of master's degree Chemical Engineering and Bioengineering Lukáš Šatura has - as a sole representative of UCT Prage - participated in student competition "SVOČ 2021" in mathematics and physics organized by the Faculty of Nuclear Sciences and Physical Engineering CTU Prague and with his work "Thermodynamically Consistent Modelling of Phase Separation Process" has placed third in section "Applied mathematics - numerical analysis and mathematical models of dynamics". Congratulations and all the best in your future career!
Many congratulations to our PhD student Martin Balouch on his publication “In-silico screening of drug candidates for thermoresponsive liposome formulations”, which has been selected for the front journal cover of Molecular Systems Design and Engineering, published by the Royal Society of Chemistry. The work, which was carried out in collaboration between VŠCHT Praha and Palacký University in Olomouc and supported by The PARC, reports on a computational methodology for the selection of active pharmaceutical ingredients that are suitable for encapsulation into liposomes based on stability, capacity and permeation rate. This computational methodology has the potential to accelerate the development process of new medicines, and improve the efficacy and bioavailability of active pharmaceutical ingredients via delivery in liposomal formulations. Well done all authors for this important piece of work!
“Our achievements rocked science in 2020. I am proud of every student in The Parc and I would like to thank all the supervisors from Zentiva and the academia for the student’s supervision and enthusiasm to solve current challenges in pharmaceutical science together. The Parc´s research clearly addresses the key challenges the pharma industry is facing today and its results are directly applied in the new products development and manufacturing” – said Ondrej Dammer, The Parc’s Operational Director.
For the third time, The Parc doctoral students were awarded The Parc Awards in two categories. Tereza Boleslavská won The Student Choice Award for her project on “Development of biorelevant in vitro dissolution method” while the second Student award went to Jan Jirát for “Crystal design and crystallization process development” and the third Student prize was awarded to Jakub Petřík for his work on “Forced degradation study system development”. The Expert Choice Award went to Jiří Kolář for his work “Mathematical modeling of unit operations in pharmaceutical formulation processes”.
Prof. František Štěpánek, The Parc’s Scientific Director commented: “I would like to congratulate the winners and all the students for their 2020 research studies and results. At The Parc we continue to provide a bridge between excellent basic research in pharmaceutical sciences and its translation to real pharmaceutical products that can be clinically tested, registered, and manufactured. Through collaboration with the best academic institutions across the EU our platform provides its Ph.D. students with the opportunity to gain first-hand experience of both academic and industrial R&D environment, thus broadening their future career prospects. It is great to acknowledge that The Parc alumni launch successful careers not only in the pharmaceutical industry and academic institutions across Europe, but this year also the first technological start-up company was founded by one of our graduates.”
Zentiva strongly believes that supporting students by bridging the gap between theoretical science and what happens in the real-life in pharma will have a valuable impact on the future careers of young people, especially members of the Z generation in the Czech Republic. The high quality of the students’ program and its practical benefits were also recognized by Prime Minister Andrej Babiš during his visit to The Parc last September.
“From the superb quality of research receiving this year´s awards, it is clearly visible that the Parc is already fulfilling its mission to build a strong foundation for further growth of the pharmaceutical industry in the Czech Republic. The unique combination of world-class academic education with practical hands-on industrial and business experience in The Parc clearly shows a functional and successful example of how to speed up the transfer of academic research into practical applications in the industry, boost the research and development activities in the companies and prepare the next generation of scientists and engineers to be ready at their graduation to tackle the industrial challenges of the future. The Parc shows one of the ways we can really deliver on the “country for future” strategy of the Czech Republic” - summarized Pavel Sebek, Zentiva's Development Director and one of the founders of The Parc.
About The Parc
Initiated by Zentiva, The Parc was created in association with three academic partners: the University of Chemistry and Technology Prague; the Faculty of Science of Charles University; and the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences. This highly successful initiative has brought rising talent together with leading pharmaceutical and academic experts, all working to accelerate innovation in drug research & development.
The Parc provides world-class academic education combined with practical hands-on industrial and business experience under the leadership of scientists, engineers, and managers both from academia and the pharmaceutical industry. It enables students to gain graduate-level training in pharmaceutical sciences bridging chemistry, pharmaceutical technology, bio pharmacy, and clinical research. Results of the students’ research are frequently directly implemented in real-world products launched to the market to help patients. Collaborating with academic partners across Europe, The Parc also offers secondments for students and research experience exchanges supervised by top academic scientists.
More information about The Parc can be found on www.theparc.eu.
Zentiva is a producer of high-quality affordable medicines serving patients in Europe and beyond. With a dedicated team of more than 4,500 people and a network of production sites - including flagship sites in Prague, Bucharest, and Ankleshwar - Zentiva strives to be the champion of branded and generic medicines in Europe to better support people’s daily healthcare needs.
At Zentiva it is our aspiration that healthcare should be a right and not a privilege. More than ever, people need better access to high-quality affordable medicines and healthcare. We work in partnership with physicians, pharmacists, wholesalers, regulators, and governments to provide the everyday solutions that we all depend on.
Source: Zentiva Press Release
Ivan Řehoř: Mikrorogel robots
Jitka Čejková - Robot 100: Sto rozumů (book)
Even in these difficult times, we decided not to break our tradition and held the regular The Parc symposium! We had 29 presenting PhD students, this time we were also joined by potential future applicants and representatives from the Pharmaceutical Faculty of Charles University, Faculty of Science of Masaryk University and Pharmaceutical Faculty of Masaryk University. We thank all the presenters and hope our guests had an enlightening experience! On the photos, you can see some of our members in their native environments...
Artificial life (commonly abbreviated Alife) is an interdisciplinary field that can be most briefly described as the study of life as it could be as opposed to the biology, which studies life as we know it here on Earth. This is a fascinating field where topics range from artificial intelligence and robotics to the chemical synthesis of artificial cells to almost philosophical considerations (what exactly is life?). In the Alife community, one encounters computer scientists, robotics researchers, physicists, chemists, biologists and also representatives from humanities disciplines and even artists. ALIFE conferences have been held annually since the 1980s, when the first conference was hosted by Christopher Langton, one of the founders of the field, in Los Alamos, United States.
Originally, this year’s conference was supposed to take place in Montreal, Canada, but due to the current situation and limited opportunities to travel, it was moved online to become the first fully virtual ALIFE conference. Next year the University of Chemistry and Technology, Prague (UCT Prague), will organize the conference. I am optimistic about the future, so we are planning ALIFE 2021 as a hybrid conference. This means that the conference will take place in Prague but that those who will not be able to in-person will be able to participate virtually. However, it will not be the first hybrid ALIFE conference: already starting in 2019 for the Newcastle (U.K.) event, scientists from the ALIFE community could choose whether to attend in-person or to choose a more environmentally friendly option by attending lectures online. We believe that the hybrid format will eventually become common for all conferences.
Although artificial life does not have much of a tradition in the Czech Republic (and currently only I and a handful of CIIRC scientists are supporters of this field), next year’s event will be the second international conference on artificial life to take place in the country. The first, ECAL (The 6th European Conference on Artificial Life), was organized by Jozef Kelemen in 2001. The ALIFE conference will therefore “return” to Prague after 20 years and its theme this time will be the celebration of the hundredth anniversary of Čapek’s R.U.R. (Rossum’s Universal Robots), source of the globally used word “robot”, which first appeared in this work.
Anyone who has read Čapek’s play or seen it in a theatre knows that Rossum’s robots were not metal monsters, as many people imagine robots imagine, but were made of chemically prepared matter that behaved as if it were alive. The play states: “Nature has found only one way to organize living matter. However, there is another way, simpler, more malleable and faster, which nature has not encountered at all.” With a little exaggeration, it could be said that Karel Čapek formulated some of the ideas and goals of the scientific field of artificial life as early as 1920. In R.U.R., we find many topics that scientists are still dealing with today: whether it is the processes of synthesis of artificial tissues and organs, questions surrounding evolution and reproduction, the ability to imitate the behaviour of human beings and to show at least signs of intelligence or consciousness. R.U.R. also outlines societal issues related to globalization, the division of power and wealth, religion, and the status of women. Basically, almost every scientist could show an example of how R.U.R. opens one of the still unanswered questions in their area of investigation. And that’s exactly what I did! At first I decided to recall how this hundred-year-old play is related to chemistry, but later I began to relate individual ideas to artificial life and other fields. I contacted my colleagues and acquaintances and asked them to read the Čapek's original R.U.R. (especially abroad, many had no idea about this work) and then to write their commentaries about it. And so the book Robot 100 was created.
From last autumn to January this year, I collected a total of 86 short chapters and several illustrations from 100 personalities—not only scientists, but also fiction writers, journalists, athletes, and artists. About a third are Czechs; the other authors come from all over the world. If we look at it like the Olympics symbol with its five interlocking rings, there are representatives from all five continents in the book. You will be able to find out who and what they contributed to the book on the website www.robot100.cz and social media. From now until November, the details about the book Robot 100 will be gradually released. And the book itself will see the light of day in November 2020, exactly one hundred years after the book edition of Čapek’s R.U.R. For now, I will tell you that the author of the cover of Robot 100 is the well-known Czech illustrator Jonáš Ledecký.
The Czech version of Robot 100 will be published by us at the UCT Prague Press. UCT Prague is the largest chemistry oriented university in the Czech Republic, which focuses not only on teaching and research in chemistry, chemical technology, biochemistry, biotechnology, and materials engineering, but also gives us, researchers, the ability to explore relatively new fields such as artificial life, as mentioned above. The UCT Prague Press, headed by Ing. Eva Dibuszová, PhD, is the only specialized publishing house in the Czech and Slovak Republics that systematically publishes chemical literature. In addition to coursepacks and textbooks, the publishing house also publishes conference proceedings and books for the general public.
It is terrific that our university’s publishing house has included Robot 100 in its publishing plan for this year. I am glad that, here at UCT Prague, we will be able to commemorate Čapek’s original concept: that his R.U.R robots originated by chemical means, and that for the first time, the word “robot” was used essentially for a chemical invention, albeit only a fictitious one. However, we are not the only ones planning to celebrate the centenary of the word “robot”. I am collaborating, for example, with Zdeněk Vacek, director of the Karel Čapek Memorial, where various events are planned in this context for autumn 2020. In January 2021, Jiří Dědeček and Jaroslav Veis will hold a several-day conference at the Archa Theater to celebrate 100 years of R.U.R. Some other authors and I will give lectures at events for the general public, especially during November’s “Night of Scientists”. I collaborate with Jana Horáková from Masaryk University in Brno, who wrote an amazing book, Robot as Robot, about R.U.R. from the theatre studies perspective. And the highlight of all this will be the ALIFE international conference, which will take place in Prague in summer. And at that time, the English version of Robot 100 will be published.
22 teachers from our department spent two half days out of Prague to intensively discuss about topics related to education and research at our Department of Chemical Engineering.
This year master students visited three companies only virtually. MS Teams platform was used for the group meeting with the absolvents of our department and representatives of Evonik (Dr. Robert Jahn), Zentiva and The Parc (Dr. Jiří Dohnal, Dr. Pavel Kovačík and Dr. David Smrčka) and Škoda (Dr. František Plát and his colleagues).
Many congratulations to the glucan team from Chemical robotics laboratory for being awarded a national patent on a new process for drug encapsulation by spray drying. The patent titled “Method of producing composite beta-glucan particles with incorporated poorly water soluble drug, pharmaceutical preparation and use thereof” by inventors Gabi Ruphuy, Petra Šalamúnová, Ivan Saloň, Jarda Hanuš and František Štěpánek has been registered under no. CZ 308357.